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CanSino vaccine good for only 6 months, study finds

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Post by MichaelB Mon May 24, 2021 6:01 pm

https://mexiconewsdaily.com/news/coronavirus/cansino-only-effective-6-months/

Booster shot will be needed after effectiveness wanes
Published on Monday, May 24, 2021
The immunity against Covid-19 provided by China’s single-shot CanSino vaccine — which has been used in Mexico to inoculate millions of seniors and teachers — declines significantly after six months, according to the results of a clinical trial.

People inoculated with the vaccine should therefore be given a booster shot, the study concluded.

According to a report by the newspaper El Universal, the National Institute of Medical Sciences and Nutrition, one of the Mexican institutions involved in the trial that began late last year, wrote to participants earlier this month to advise them that immunity against Covid-19 generated by the CanSino shot had been found to wane “significantly” after six months. It didn’t specify what it meant by significantly.

The CanSino vaccine had been found to be about 75% effective against the coronavirus and 100% effective against serious disease.

The medical institute’s email message to trial participants said they would be given a second CanSino dose if they had already received a first shot. Those who received a placebo will be given a first shot of the CanSino vaccine and a second shot six months later, the email said.

El Universal asked the federal Health Ministry what the study’s finding would mean for the government’s national vaccination program but the ministry didn’t respond to the newspaper’s request for comment.

As of Sunday night, Mexico had received 4.6 million doses of CanSino, a figure that accounts for about 14% of all shots delivered. The government last year signed an agreement to purchase 35 million doses of the shot, one of two Chinese-made vaccines that have been used in Mexico.

If the government follows the advice based on the findings of the clinical trial, all people who have already had a CanSino shot will have to get another one before the end of the year. The number of people who can be inoculated with the CanSino shots Mexico has agreed to buy would be halved from 35 million to 17.5.

The CanSino vaccine is not the only Covid-19 vaccine for which a booster shot is likely to be required. Pfizer CEO Albert Bourla said last month that people inoculated with that company’s product would likely need a third booster dose.

“A likely scenario is that there will be likely a need for a third dose, somewhere between six and 12 months and then from there, there will be an annual revaccination, but all of that needs to be confirmed. And again, the variants will play a key role,” he said April 1.

Johnson & Johnson CEO Alex Gorsky told CNBC in February that annual vaccination against Covid-19 might be necessary, as is the case with the seasonal flu.

Mexico has received almost 33.5 million doses of five different vaccines, according to data presented at the Health Ministry’s Sunday night coronavirus press briefing. The government has received 13.4 million Pfizer shots, 6 million doses of AstraZeneca, 7 million SinoVac vaccines, 2.4 Sputnik V shots and 4.6 million doses of CanSino.

Just under 26.5 million of the doses, or about 80% of those received, had been administered by Sunday night.

Mexico’s coronavirus situation has improved significantly since the country went through its second and worst wave of the pandemic, which began late last year and extended into early 2021. Half of Mexico’s 32 states are now low-risk green on the federal stoplight map, 15 are medium risk yellow and just one — Quintana Roo — is high-risk orange.

Mexico’s accumulated case tally is currently 2.39 million, while the official Covid-19 death toll is 221,647, a figure considered a vast undercount.

Source: El Universal (sp), CNBC (en)

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Post by Gamina Tue May 25, 2021 10:55 pm

"The immunity against Covid-19 provided by China’s single-shot CanSino vaccine — which has been used in Mexico to inoculate millions of seniors and teachers — declines significantly after six months, according to the results of a clinical trial."

This headline will get people all excited and upset but the article is about the ONE SHOT CanSino vaccine, which wasn't administered at Lakeside.
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Post by ComputerGuy Tue May 25, 2021 11:09 pm

All teachers lakeside got the CanSino this month. And the report has already been debunked. Who knows?
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Post by Henry1944 Wed May 26, 2021 7:55 am

ComputerGuy wrote:All teachers lakeside got the CanSino this month. And the report has already been debunked. Who knows?

Really? Where? I read Pakistan reporting the same results. I'm assuming no one would believe what the Chinese have to say about this, or anything else for that matter.

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Post by ferret Wed May 26, 2021 8:21 am


Posted May 18 on TOB by Bisbee Gal and includes a link...

The CanSino for teachers was pretty well known. But thanks for explaining why it was included in your post.

https://theguadalajarareporter.net/index.php/news/news/regional/56674-cristiania-park-hosts-shots-for-academic-sector

Cristianía Park hosts shots for academic sector

Published: 29 April 2021 Written by Dale Hoyt Palfrey
Chapala was chosen as one of 13 venues for inoculations against the SARS-CoV-2 virus scheduled April 28 through May 4 for teachers and administrative staff of Jalisco’s public and private educational institutions.


MORE THAN 1,000 TEACHERS AND SCHOOL ADMINISTRATORS WERE SIGNED UP FOR THE FIRST DAY OF CANSINO SHOTS POKED INTO ARMS AT CHAPALA’S CRISTIANÍA PARK. WITH LOGISTICS WORKED OUT WELL IN ADVANCE, THE CLINIC WAS UP AND RUNNING FROM THE GET-GO WEDNESDAY, APRIL 28.

The city’s La Cristianía Park headquartered vaccinations for academic personnel employed in Chapala, Jocotepec and nine other municipalities in the Southeast Region, plus neighboring Ixtlahuacán de los Membrillos. Finely tuned logistics implemented early Wednesday, April 28, translated into efficient, trouble-free operation of the clinic for the 1,065 individuals scheduled to attend on that date.

According to site coordinator Oscar Diaz Zambrano, regional delegate for the state’s Education Department (SEP), operative wrinkles were worked out during trial runs on Monday and Tuesday. Opening up promptly at 8 a.m. on Wednesday, the first group of patients quickly got through checking of their registration documents to get their jabs within 25 minutes. Large tents were placed outside at the park’s entrance, as the initial waiting area, with three tented vaccination modules located inside the gates.

The program for application of single-dose CanSino vaccines was organized entirely by SEP and the Universidad de Guadalajara, without involving the federal government’s Servants of the Nation. The local clinic was supported by 70 SEP employees and another 50 staffers from Chapala City Hall.
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Post by ComputerGuy Wed May 26, 2021 8:29 am

Henry1944 wrote:
ComputerGuy wrote:All teachers lakeside got the CanSino this month. And the report has already been debunked. Who knows?

Really?  Where?  I read Pakistan reporting the same results.  I'm assuming no one would believe what the Chinese have to say about this, or anything else for that matter.

Like I said, who knows.


https://www.elfinanciero.com.mx/salud/2021/05/25/cansino-aclara-que-efectividad-de-vacuna-covid-no-se-pierde-en-6-meses/

CanSino clarified on Tuesday that the effectiveness of its vaccine against COVID-19 is not lost six months after its application.

The pharmacist pointed out that "a communication error" caused this information to be given to participants in the phase 3 trial carried out in Mexico.

CanSino stressed that all vaccines against the new coronavirus are still in development and therefore, there is no certainty about how long their effectiveness lasts.

"We do have the certainty that at some point each and every one will have to be reinforced, " he said in a statement.

The company added that it is not yet known how much this reinforcement will be applied, but the date will be reported "as soon as we have the necessary data."
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Post by ferret Wed May 26, 2021 8:40 am

I also think that IF they are just measuring antibodies then it's a false premise to say that one is not protected.
Nobody keeps antibodies circulating forever... not to anything.
Your body produces T cells and B cells that "remember" and they kick up personal production of antibodies when a "villain" is encountered again.
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Post by lunateak Sat Jun 19, 2021 2:34 pm

Gamina wrote:"The immunity against Covid-19 provided by China’s single-shot CanSino vaccine — which has been used in Mexico to inoculate millions of seniors and teachers — declines significantly after six months, according to the results of a clinical trial."

This headline will get people all excited and upset but the article is about the ONE SHOT CanSino vaccine, which wasn't administered at Lakeside.

Yes, it was. Yes, I received it.
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Post by LoveSouth Wed Jun 23, 2021 4:19 am

Oh, for God’s sake: something else to fret over! I got the CanSino jab back in April in Ixtlahuacan, and quietly wondered when I’d have to line up for a booster. Let’s advise everyone about booster availability and dates later this year…in true InsideLakeside forum bonhomie. And cheers to you all, as always, for your (usually) sage advice.

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